| Autor: |
Verboon-Maciolek, M.A., Nijhuis, M., Pekelharing-Berghuis, M.A., Krediet, T.G., Gerards, L.J., Fleer, A., Diepersloot, R.J.A., Thijsen, S.F.T., van Loon, A.M., van Maarssenveen, N., van Wieringen, H. |
| Předmět: |
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| Zdroj: |
Clinical Infectious Diseases; 7/1/2003, Vol. 37 Issue 1, p1, 6p |
| Abstrakt: |
During summer and fall, enterovirus infections are responsible for a considerable proportion of hospitalizations of young infants. We prospectively studied the incidence of enterovirus infections via real-time polymerase chain reaction (PCR) in blood, feces, and cerebrospinal fluid samples from infants ⩽ 60 days old who had received a clinical diagnosis of sepsis. Forty-five patients were included: 19 were admitted to the pediatric wards of 2 general hospitals, and 26 had been hospitalized since birth in the neonatal intensive care unit (NICU) of a tertiary care hospital. None of the NICU patients developed enteroviral disease. In contrast, an enterovirus was detected in 11 (58%) of the patients admitted to the 2 general hospitals, 10 of whom (53%) showed evidence of systemic infection. Enterovirus infections are an important cause of sepsis in infants admitted to the hospital. Real-time PCR in serum was a rapid and sensitive method for diagnosis of enterovirus infection. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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