Pheomelanin-coated iron oxide magnetic nanoparticles: a promising candidate for negative T2 contrast enhancement in magnetic resonance imaging.

Autor: Zottis, Alexandre D. A., Beltrame, Jeovandro M., Lara, Luciano R. S., Costa, Thiago G., Feldhaus, Mateus J., Pedrosa, Rozangela Curi, Ourique, Fabiana, de Campos, Carlos E. M., Isoppo, Eduardo de A., da Silva Miranda, Fabio, Szpoganicz, Bruno
Předmět:
Zdroj: Chemical Communications; 7/18/2015, Vol. 51 Issue 56, p11194-11197, 4p
Abstrakt: We describe herein a novel type of monodisperse water-soluble magnetite nanoparticle coated with pheomelanin using an environmentally-friendly approach in aqueous medium. The results indicate superparamagnetic behaviour at room temperature and show improved negative contrast in T2-weighted MRI with a transverse relaxivity of 218 mM−1 s−1. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index