| Autor: |
Yingfa Li, Cooksey, John P., Zhanghua Gao, Kocieński, Philip J., McAteer, Stephen M., Snaddon, Thomas N. |
| Předmět: |
|
| Zdroj: |
Synthesis; 2011, Vol. 2011 Issue 1, p104-108, 5p |
| Abstrakt: |
Key steps in a synthesis of the C17-C32 fragment of ionomycin are (a) an auxiliary-directed oxidative cyclisation of a diene with potassium permanganate to construct a tetrahydrofuran ring and four stereogenic centres in a single operation, and (b) a chainappendage reaction featuring the alkylation of an enolsilane by an oxocarbenium ion generated from a 2-phenylsulfonyl-substituted tetrahydrofuran. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
