In vitro microbiological evaluation of novel 2-oxo-2H-chromene-3-carbaldehyde containing 1,3,4-thiadiazole moiety.

Autor: Govori, Sevdije, Spahiu, Sabrie, Haziri, Arben
Předmět:
Zdroj: Toxicological & Environmental Chemistry; Oct2014, Vol. 96 Issue 9, p1366-1373, 8p
Abstrakt: 4-(5-(Methylthio)-1,3,4-thiadiazol-2-ylamino)-2-oxo-2H-chromene-3-carbaldehyde (3) and 4-(5-(ethylthio)-1,3,4-thiadiazol-2-ylamino)-2-oxo-2H-chromene-3-carbaldehyde (4) were prepared. The structures of the newly synthesized compounds were characterized by infrared (IR), nuclear magnetic resonance (NMR) spectral data and elemental analysis. The synthesized compounds were screenedin vitrofor their antibacterial activities. The synthesized compounds demonstrated moderate antimicrobial activity. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index