| Autor: |
Boner, A. L., Vici, E. Folchi, Carcereri, L., Sette, L., Bonizzato, C. |
| Předmět: |
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| Zdroj: |
Pediatric Allergy & Immunology; Dec1991, Vol. 2 Issue 4, p165-169, 5p |
| Abstrakt: |
Spontaneous histamine release from basophils was evaluated in children with atopic dermatitis and in healthy controls. Patients were divided into 2 groups, one with specific IgE antibodies for food allergens (Group 1) and one without specific reaginic antibodies (Group 2). Group 1 showed significantly higher histamine release (median 7.25%) than Group 2 (median 4.2%) and healthy controls (median 2.05%). Histamine release was also significantly greater in Group 2 patients compared with healthy controls (p < 0.005). Group 1 was studied again after an exclusion diet which resulted in an improvement of symptoms and a significant reduction (p < 0.001) of histamine release. Children with atopic dermatitis both with and without IgE antibodies for food allergens present a degree of "basophil hyperreactivity" which decreases after an appropriate exclusion diet in children with associated food allergy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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