Synthesis of (±)-15-deoxy-Δ-prostaglandin J and Δ-prostaglandin J 15-acetate methyl esters.

Autor: Vostrikov, N., Lobko, I., Ishimova, D., Miftakhov, M.
Předmět:
Zdroj: Russian Journal of Organic Chemistry; Jan2015, Vol. 51 Issue 1, p1-9, 9p
Abstrakt: A new synthetic approach to 15-deoxy-Δ-prostaglandin J and related compounds starting from Corey (±)-lactone diol has been developed. The key stage of this approach includes synthesis of a prostaglandin derivative possessing leaving groups in positions 9, 13, and 15 and their subsequent elimination by the action of an organic base. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index