Autor: |
Zirbs, M., Anzeneder, T., Bruckbauer, H., Hofmann, H., Brockow, K., Ring, J., Eberlein, B. |
Předmět: |
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Zdroj: |
Journal of the European Academy of Dermatology & Venereology; May2015, Vol. 29 Issue 5, p904-911, 8p |
Abstrakt: |
Background Up to present no curative treatment is known for Dupuytren's disease (DD). Surgery remains the most common treatment but lack of long-term efficacy and complications limit this therapeutic option. Objective In a retrospective analysis, the results of radiotherapy with soft X-rays in the treatment of DD were evaluated. Methods A total of 206 patients (297 affected hands) with DD were included. Radiation therapy was carried out with soft X-rays. A structured questionnaire considering patient and disease characteristics and effects of radiotherapy was evaluated after a median follow-up time of 40 months. Results Ninety-three (45%) of the 206 treated patients were reported on a regression of symptoms after radiation. No further disease progression (including patients with regression) was present in 165 patients (80%). Satisfaction with the therapy was expressed with an average score of 7.9 points (visual analogue scale, 0 = not satisfied, 10 = extremely satisfied). Subjective therapeutic effects for 426 nodules and/or cords showed a reduction of 92 nodules and/or cords. Conclusion In 206 DD patients further disease progression was stopped in most patients. Radiotherapy proved to be well-tolerated, successful and satisfying for the patients. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
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