Click Chemistry with 2-Ethynyl-4,5,6,7-tetrahydroindoles: Towards Functionalized Tetrahydroindole-Triazole Ensembles.

Autor: Sobenina, Lyubov N., Tomilin, Denis N., Ushakov, Igor A., Mikhaleva, Albina I., Sh. Ma, J., Yang, G., Trofimov, Boris A.
Předmět:
Zdroj: Synthesis; Mar2013, Vol. 45 Issue 5, p0678-0682, 5p
Abstrakt: 2-Ethynyl-4,5,6,7-tetrahydroindoles, readily available from 4,5,6,7-tetrahydroindoles and bromoacetylenes on K2CO3, when treated with sodium azide in DMSO, afford functionalized tetrahydroindole-triazoles ensembles. The reaction proceeds under mild conditions (room temperature) to give triazoles with acyl or ester moieties in quantitative yields. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index