Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN 8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
| Autor: | Ning-Kui Niu, Zi-Li Wang, Shu-Ting Pan, Hui-Qiang Ding, Giang HT Au, Zhi-Xu He, Zhi-Wei Zhou, Guozhi Xiao, Yin-Xue Yang, Xueji Zhang, Tianxin Yang, Xiao-Wu Chen, Jia-Xuan Qiu, Shu-Feng Zhou |
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| Zdroj: | Drug Design, Development & Therapy; 2015, Vol. 9, p1555-1584, 30p |
| Databáze: | Complementary Index |
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