Hospital-based surveillance of invasive pneumococcal disease and pneumonia in South Bangalore, India.

Autor: Nisarga, Ramalingowda, Premalatha, R., Shivananda, Ravikumar, K., Shivappa, U., Gopi, A., Chikkadasarahalli, S., Batuwanthudawe, R., Kilgore, P., Kim, S., Balter, I., Jouve, S., Ye, J., Moscariello, M.
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Zdroj: Indian Pediatrics; Mar2015, Vol. 52 Issue 3, p205-211, 7p
Abstrakt: Objective: To estimate the incidence of invasive pneumococcal disease and pneumonia, distribution of pneumococcal serotypes, and antibiotic susceptibility in children aged 28 days to <60 months. Design: Hospital-based surveillance. Setting: South Bangalore, India. Participants: 9950 children aged 28 days to <60 months with clinical suspicion of invasive pneumococcal disease or pneumonia. Results: The estimated at-risk population included 224,966 children <5 years of age. Forty cases of invasive pneumococcal disease were identified. Estimated invasive pneumococcal disease incidence was 17.8/100,000 with incidence being highest among children aged 6 months to <12 months (49.9/100,000). Clinical pneumonia syndrome was the most frequent diagnosis (12.5/100,000). Pneumococcal serotypes included: 6A ( n=6, 16.7%); 14 ( n=5, 13.9%); 5 ( n=4, 11.1%); 6B ( n=4, 11.1%); 1, 18C, and 19A ( n=3 each, 8.3%); 9V ( n=2, 5.6%); and 3, 4, 10C, 18A, 18F, and 19F ( n=1 each, 2.8%). Serotypes 6A, 14, 6B, 1, 18C, 19A, 9V, 4, 10C, and 18A showed antibiotic resistance. Clinical pneumonia incidence was 2109/100,000, with incidence being highest among children aged 28 days to <6 months (5033/100,000). Chest radiograph-confirmed pneumonia incidence was 1114/100,000, with incidence being highest among children aged 28 days to <6 months (2413/100,000). Conclusion: Invasive pneumococcal disease and pneumonia were found to be common causes of morbidity in young children living in South Bangalore, India. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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