iso-Petromyroxols: Novel Dihydroxylated Tetrahydrofuran Enantiomers from Sea Lamprey (Petromyzon marinus).

Autor: Ke Li, Brant, Cory O., Bussy, Ugo, Pinnamaneni, Harshita, Patel, Hinal, Hoye, Thomas R., Weiming Li
Předmět:
Zdroj: Molecules; Mar2015, Vol. 20 Issue 3, p5215-5222, 8p, 2 Diagrams, 1 Chart, 2 Graphs
Abstrakt: An enantiomeric pair of new fatty acid-derived hydroxylated tetrahydrofurans, here named iso-petromyroxols, were isolated from sea lamprey larvae-conditioned water. The relative configuration of iso-petromyroxol was elucidated with 1D and 2D NMR spectroscopic analyses. The ratio of enantiomers (er) in the natural sample was measured by chiral-HPLC-MS/MS to be ca. 3:1 of (-)- to (+)-antipodes. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index