Synthesis of oxazolidine-2,4-diones by a tandem phosphorus-mediated carboxylative condensation–cyclization reaction using atmospheric carbon dioxide.

Autor: Zhang, Wen-Zhen, Xia, Tian, Yang, Xu-Tong, Lu, Xiao-Bing
Předmět:
Zdroj: Chemical Communications; 4/11/2015, Vol. 51 Issue 28, p6175-6178, 4p
Abstrakt: The oxazolidine-2,4-dione motif is found frequently in biologically important compounds. A tandem phosphorus-mediated carboxylative condensation of primary amines and α-ketoesters/base-catalyzed cyclization reaction have been developed. These processes provide a novel and convenient access to various oxazolidine-2,4-diones in a one-pot fashion using atmospheric carbon dioxide and readily available substrates under very mild and transition-metal-free conditions. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index