| Autor: |
Santos, Carlos Eduardo Oliveira, Malaman, Daniele, Mönkemüller, Klaus, Santos Carvalho, Tiago, Lopes, César Vivian, Pereira‐Lima, Júlio Carlos |
| Předmět: |
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| Zdroj: |
Digestive Endoscopy; Mar2015, Vol. 27 Issue 3, p361-367, 7p |
| Abstrakt: |
Background and Aim Several studies suggest that non-polypoid lesions ( NPL) show higher aggressiveness than polypoid lesions, particularly depressed lesions. The present study aimed to assess the prevalence of NPL and the presence of advanced histology in a Brazilian population. Methods Two thousand and sixty-seven superficial neoplastic lesions diagnosed in 1135 patients were analyzed. Lesions were classified as polypoid and non-polypoid (flat and depressed) types, and evaluated for site, size, and histology (adenoma with grade of dysplasia, or early cancer). Results Prevalence of NPL was 46.5%. NPL predominated in the right colon (62.9%), whereas polypoid lesions were detected mainly in the left colon (53.2%) ( P < 0.001). NPL had a 34% higher probability of occurring in the right colon than polypoid lesions ( P < 0.001). NPL were smaller than polypoid lesions ( P = 0.03). There were 208 lesions >10 mm, of which 40 (19.2%) had advanced histology: 13% (18/138) of polypoid lesions; 27.3% (18/66) of flat lesions; and 100% (4/4) of depressed lesions ( P < 0.001). Among 1859 neoplasms ≤10 mm, only 18 (1%) had advanced histology, and 15 of them were depressed lesions ( P < 0.001). Advanced histology was more commonly detected in NPL than in polypoid lesions ( P = 0.007), with significant difference in size ( P < 0.001). NPL showed more advanced histology than polypoid lesions ( OR 2.06; P = 0.01), especially depressed lesions ( OR 36.35; P < 0.001). Among all neoplasms, the prevalence of depressed lesions was 2.2%. Conclusion NPL showed high prevalence and higher aggressiveness than polypoid lesions, especially the depressed type. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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