| Abstrakt: |
Objective To investigate the efficacy and safety of endoscopic naso-pancreatic drainage (ENPD) in treatment of acute pancreatitis (AP) with large pseudocyst. Methods A total of 57 AP patients with large pancreatic admitted from June 2010 to June 2013 at the First Affiliated Hospital of Chongqing Medical University were enrolled and divided into the ENPD group (29 cases)and the control group(28 cases). The patients in the control group were received conservative therapy while the ENPD group added ENPD treatment based on the conservative therapy. The cilinic effects and complications of the two groups were analyzed. Results In ENPD group,two patients failed to torlerate the ENPD to transfer to the percutaneous catheter drainage (PCD) on the 2nd and 5th days after drainage respectively. The duration of abdominal release pain,hospitalization,normalization of body temperature and white blood cells recovery were shorter than those of the control group[(9.30±2.37), (26.3±5.36), (8.59±3.27), vs. (14.2±2.99), (36.8±3.59), (13.4±3.27)] and the surgical operation rate and morality were lower in the ENPD group than in conservative therapy group[11.1% (3/27),0 (0/27)vs. 32.1O (9/28), 14.3O (4/28)],whose difference had statistical significance (P<0.05). Three patients occurred infection during ENPD course, but no perforation and bleeding occurred and drainage was complete (The pseudocyst was not found out under CT). Conclusions ENPD is avaiable to relieve the pressure of ancreatic duct, control the pancreatitis progress and reduce the occurrence of complications, which is more effective and safe in treatment of huge pancreatic pseudocyst. [ABSTRACT FROM AUTHOR] |
