| Autor: |
Zanatta, Nilo, Fortes, Andressa S., Bencke, Carlos E., Marangoni, Mário A., Camargo, Adriano F., Fantinel, Cassio A., Bonacorso, Helio G., Martins, Marcos A. P. |
| Předmět: |
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| Zdroj: |
Synthesis; 2015, Vol. 47 Issue 6, p827-835, 9p |
| Abstrakt: |
A simple and efficient procedure for the synthesis of ethyl 2- methylthio- and ethyl 2-benzylthio-6-methyl(aryl)-pyrimidine-4-carboxylates and their corresponding acid derivatives is reported. The products are obtained in good yields via the cyclocondensation reaction of ethyl 4-alkoxy-2-oxo-4-methyl(aryl)-but-3-enoates with 2-methylisothiourea sulfate or 2-benzylisothiourea hydrochloride, under mild, basic, aqueous conditions. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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