Bis(indolyl)methanes Synthesis Through Sodium Iodate and Sodium Hydrogen Sulfite in Water.

Autor: Mohammed Khan, Khalid, Rahim, Fazal, Ali Shah, Syed Adnan, Taha, Muhammad, Ismail, Nor Hadiani, Manzoor, Mehwish, Abbas Miana, Ghulam, Perveen, Shahnaz
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Zdroj: Journal of the Chemical Society of Pakistan; 12/31/2015, Vol. 36 Issue 6, p1158-1161, 4p
Abstrakt: An effective and eco-friendly method for the bis(indolyl)methanes synthesis has been developed. A successive methodology involving sodium iodate/sodium hydrogen sulfite catalyzed reaction of indole with many aldehydes gave the resultant bis-indol in good yield. This method offers synthetically inexpensive alternate to the previously developed procedures for the bis-indol synthesis. The use of a low-cost and straightforwardly accessible catalyst, improved yields and a simple reaction process are the salient features of the current method. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index