| Autor: |
Garner, Amanda L., Yu, Jing, Struss, Anjali K., Kaufmann, Gunnar F., Kravchenko, Vladimir V., Janda, Kim D. |
| Předmět: |
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| Zdroj: |
Chemical Communications; 2013, Vol. 49 Issue 15, p1515-1517, 3p |
| Abstrakt: |
As a guide for chemical probe design, focused analogue synthetic studies were undertaken upon the lactone ring of 3-oxo-C12-homoserine lactone. We have concluded that hydrolytic instability of the heterocyclic ring is pivotal for its ability to modulate immune signaling and probe preparation was aligned with these findings. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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