| Abstrakt: |
Introduction: The non-invasive respiratory support, type CPAP, is widely used to support respiratory function in preterm infants and it is often the first choice in the neonatal intensive care unit. Aim of the study: The aim of the study is to compare two therapeutic approaches to respiratory distress syndrome due to surfactant deficiency in premature infants. Material and method: In this study were included all premature infants with gestational age up to 29 weeks, who were treated in the Intensive Care Unit within Oradea Maternity Hospital between 01st of January 2010 and 31st of December 2013. In the study were included 141 infants, divided into two groups: for the infants in the first group the prophylactic surfactant was administered within the first 30 minutes after birth and the infants in the second group received CPAP immediately after birth. Results and Conclusions: This study presents the fact that the prophylactic surfactant reduces the duration of the CPAP respiratory therapy, of the mechanical ventilation and of the oxygen therapy. Most of these infants, from these two groups, didn't require CPAP conversion into assisted ventilation. The respiratory recovery was good in our study in both groups. The survival rate was of 68% in the first group, respectively 62,12% in the second group and the survival rate in the absence of oxygen at the corrected age of 36 weeks was of 62,66% in the first group and of 56% in the second group. The incidence of bronchopulmonary dysplasia was of 4% in the first group, respectively of 7,5% in the second group. The incidence of pneumothorax and of sepsis was higher in the group of infants with selective surfactant. In conclusion, in premature infants with gestational age between 26-29 weeks with spontaneous breathing movements, the CPAP respiratory support must be used immediately after birth and the surfactant therapy should be introduced at the first clinical, laboratory and radiological signs of respiratory distress. Using this strategy, there are obtained the maximum benefits from this respiratory therapeutic method, reducing the incidence of respiratory morbidity. [ABSTRACT FROM AUTHOR] |
