Ultrasound promoted and SiO/CClCOOH mediated synthesis of 2-aryl-1-arylmethyl-1 H-benzimidazole derivatives in aqueous media: An eco-friendly approach.

Autor: KUMAR, BRAJESH, SMITA, KUMARI, KUMAR, BRAJENDRA, CUMBAL, LUIS
Předmět:
Zdroj: Journal of Chemical Sciences; Nov2014, Vol. 126 Issue 6, p1831-1840, 10p
Abstrakt: Ultrasonic irradiation is an efficient and innocuous technique of reagent activation for synthesizing organic compounds. First one-pot synthesis of 2-aryl-1-arylmethyl-1H- benzimidazole derivatives from o- phenylenediamine and an aromatic aldehyde in the presence of silica gel supported trichloroacetic acid (SiTCA) was carried out with excellent yields at 50C by sonication. This method provided several advantages such as green solvent, inexpensive catalyst, simple experimental methodology, shorter reaction time and higher yield. [Figure not available: see fulltext.] [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index