Antioxidant and α-amylase inhibitory activities of extract and isolates from Zygogynum pancheri subsp. arrhantum.
| Autor: | Keskes, Henda, Litaudon, Marc, Cherif, Atef, Belhadj, Sahla, Hamdi, Besma, El Feki, Abdelfattah, Dumontet, Vincent, Ben Salah, Abdelhamid, Damak, Mohamed, Allouche, Noureddine |
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| Předmět: |
ACARBOSE
AMYLASES ANTIOXIDANTS BIOLOGICAL assay CRYSTALLOGRAPHY MASS spectrometry MOLECULAR structure NUCLEAR magnetic resonance spectroscopy PHARMACEUTICAL chemistry PHENOLS TERPENES THIN layer chromatography VITAMIN E PLANT extracts FREE radical scavengers FLAVONES DESCRIPTIVE statistics CHEMICAL inhibitors |
| Zdroj: | Journal of Asian Natural Products Research; Dec2014, Vol. 16 Issue 12, p1132-1138, 7p |
| Abstrakt: | One new sesquiterpenoid (5R*,8R*,9R*,10R*)-cinnamolide (8), and seven known compounds, 5-hydroxy-7-methoxyflavonone (1), 8-hydroxy-3-(4′-hydroxyphenyl)-6,7-(2″,2″-dimethylchromene)-tetralone (2), 8-hydroxy-3-(3′,4′-dihydroxyphenyl)-6,7-(2″,2″-dimethylchromene)-tetralone (3), 1β-E-O-p-methoxycinnamoyl-bemadienolide (4), 1β-O-(E-cinnamoyl)-6α-hydroxy-9-epi-polygodial (5), 1β-O-(E-cinnamoyl)-6α-hydroxypolygodial (6), and 1β-O-E-cinnamoylpolygodial (7) were isolated from the ethyl acetate extract of barks of Zygogynum pancheri subsp. arrhantum (Winteraceae). The structures of these molecules were assigned predominantly based on spectral data. The structure of compound 8 was confirmed by X-ray crystallographic analysis. Compounds 2 and 3 exhibited significant antioxidant activity, whereas compounds 1 and 4–7 showed significant α-amylase inhibitory activity. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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