Low coherence interferometry approach for aiding fine needle aspiration biopsies.

Autor: Chang, Ernest W., Gardecki, Joseph, Pitman, Martha, Wilsterman, Eric J., Patel, Ankit, Tearney, Guillermo J., Iftimia, Nicusor
Předmět:
Zdroj: Journal of Biomedical Optics; Nov2014, Vol. 19 Issue 11, p1-10, 10p
Abstrakt: We present portable preclinical low-coherence interference (LCI) instrumentation for aiding fine needle aspiration biopsies featuring the second-generation LCI-based biopsy probe and an improved scoring algorithm for tissue differentiation. Our instrument and algorithm were tested on 38 mice with cultured tumor mass and we show the specificity, sensitivity, and positive predictive value of tumor detection of over 0.89, 0.88, and 0.96, respectively. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index