An ensemble of aptamers and antibodies for multivalent capture of cancer cells.

Autor: Jinling Zhang, Weian Sheng, Fan, Z. Hugh
Předmět:
Zdroj: Chemical Communications; 2014, Vol. 50 Issue 51, p6722-6725, 4p
Abstrakt: We developed an optimized ensemble of aptamers and antibodies that functions as a multivalent adhesive domain for the capture and isolation of cancer cells. When incorporated into a microfluidic device, the ensemble showed not only high capture efficiency, but also superior capture selectivity at a high shear stress (or high flow rate). [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index