| Autor: |
Draghici, Bogdan, Akocak, Suleyman, Walker, Ellen A., Ilies, Marc A., Vullo, Daniela, Supuran, Claudiu T. |
| Předmět: |
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| Zdroj: |
Chemical Communications; 6/7/2014, Vol. 50 Issue 45, p5980-5983, 4p |
| Abstrakt: |
A series of ethylene bis-imidazoles was synthesized via a novel microwave-mediated synthesis. Biological testing on eight isozymes of carbonic anhydrase (CA) present in the human brain revealed compounds with nanomolar potency against CA VA and CA VII, also displaying excellent selectivity against other CA isozymes present in this organ. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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