| Autor: |
Wawrzyniak-Turek, Katarzyna, Höbartner, Claudia |
| Předmět: |
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| Zdroj: |
Chemical Communications; 2014, Vol. 50 Issue 75, p10937-10940, 4p |
| Abstrakt: |
We describe a general and simple method to identify catalytically and structurally important nucleotides in functional RNAs. Our approach is based on statistical replacement of each nucleoside with a non-nucleosidic spacer (C3 linker, D), followed by separation of active library variants and readout of interference effects by analysis of enzymatic primer extension reactions. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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