| Abstrakt: |
Objective To study the correlation between tall-related diseases and hip fracture among the elderly women. Methods A total of 1100 women, who were over 45 years old and had hip fractures, were identified from health insurance claims in Nagasaki Prefecture in Japan. At the same time, a age-matched (within 5-year age groups) control patient was randomly selected for each patient with hip fracture. Diseases such as hip fracture and the fall-related diseases were coded following the International Classification of Diseases, 10th Revision (ICD-10). The prevalence of visual impairment, stroke, musculoskeletal diseases, Parkinson's disease, cognitive impairment, depression, and the number of these risk factors were compared between patients with hip fractures and controls using the Chi-square test. The strength of the association between risk factors and hip fracture was estimated using a conditional Logistic regression model. Results Over 75% women with hip fracture were over 80 years old. Women with hip fracture had a significantly higher prevalence of ocular diseases (14.25% vs. 8.66%, P < 0.001, stroke(14.07% vs. 9.92%, P = 0.002 ), musculoskeletal diseases (43.91% vs. 38.77%, P < 0.001), Parkinson's disease (5.86% vs. 1.53%, P < 0.001), cognitive impairment (11.45% vs. 4.33%, P < 0.001), and depression (13.89% vs. 5.86%, P < 0.001) than those in controls. The results of conditional Logistic regression showed that ocular diseases (OR = 1.49, 95% CI: 1.13, 1.98), stroke (OR = 1.29, 95% CI: 0.98, 1.69), musculoskeletal diseases (OR = 1.29, 95% CI: 1.08, 1.54), Parkinson's disease (OR = 3.33, 95% CI: 1.87, 5.92), cognitive impairment (OR = 2.46, 95% CI: 1.72, 3.52), and depression (OR = 2.09, 95% CI: 1.54, 2.85) were significantly associated with hip fracture. Women with multiple risk factors were at higher risk of the hip fractures. Conclusion Fall-related diseases play an important role in hip fracture among the middle-aged and elderly women. Positive prevention and treatment of the fall-related diseases may contribute to lower the risks of hip fracture. [ABSTRACT FROM AUTHOR] |
