Trifluoromethylation of arenediazonium salts with fluoroform-derived CuCF3 in aqueous media.

Autor: Lishchynskyi, Anton, Grushin, Vladimir V., Berthon, Guillaume
Předmět:
Zdroj: Chemical Communications; 2014, Vol. 50 Issue 71, p10237-10240, 4p
Abstrakt: A new protocol has been developed for trifluoromethylation of arenediazonium salts with moisture-sensitive CuCF3 (from fluoroform) in aqueous media. The reaction is governed by a radical mechanism, tolerates a broad variety of functional groups, and is applicable to the synthesis of complex, polyfunctionalized molecules. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index