Review of the prevalence of diabetic retinopathy in Indigenous Australians.

Autor:	Kaidonis, Georgia, Mills, Richard A, Landers, John, Lake, Stewart R, Burdon, Kathryn P, Craig, Jamie E
Předmět:	DIABETIC retinopathy DISEASE prevalence DIABETES complications EYE diseases GLYCEMIC index AUSTRALIANS HEALTH
Zdroj:	Clinical & Experimental Ophthalmology; Dec2014, Vol. 42 Issue 9, p875-882, 9p
Abstrakt:	The purpose of this review is to compare the prevalence of diabetic retinopathy ( DR) between Indigenous and non-Indigenous Australians with Diabetes Mellitus ( DM). Australian DR prevalence data from 6 Indigenous studies ( n = 2865) and 5 non-Indigenous studies ( n = 9801) conducted between 1985 and 2013 were included for analysis. Estimated prevalence of any DR among Indigenous Australians with DM was 23.4% compared with 28.9% for non-Indigenous Australians (χ2 = 26.9, P < 0.001). In studies performed after 1990, a significantly higher rate of diabetic macular edema was found in Indigenous compared with non-Indigenous Australians with DM (7.6% versus 4.9%, χ2 = 6.67, P = 0.01). Although there are limitations in comparing these studies, one explanation for the observed data could be a model in which Indigenous Australians are relatively resistant to early stage DR, but with a subset progressing to sight threatening DR due to individual genetic and environmental susceptibility factors coupled with poor glycemic control. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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