Autor: |
Meyers MJ; Department of Chemistry, University of Illinois, Urbana 61801, USA., Carlson KE, Katzenellenbogen JA |
Jazyk: |
angličtina |
Zdroj: |
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 1998 Dec 15; Vol. 8 (24), pp. 3589-94. |
DOI: |
10.1016/s0960-894x(98)00652-0 |
Abstrakt: |
A series of styrylpyridine derivatives containing two phenols was prepared via an efficient two-step synthesis. These compounds were designed to maximize the estrogen receptor binding affinity of a known series of inherently fluorescent styrylpyridines. While significant improvements were achieved in receptor affinity, the fluorescence intensity of this series of compounds is poor. |
Databáze: |
MEDLINE |
Externí odkaz: |
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