Clinical presentation of HIV infection in patients aged 50 years or older.

Autor: Ena J; Internal Medicine Division of Hospital Marina Baixa, Villajoyosa, Alicante, Spain., Valls V, López Aldeguer J, García Gascó MP, Añón S, Navarro V, Sánchez R, Boix V, Portilla J, Roig P, Masiá MM, Maestre Peiró A
Jazyk: angličtina
Zdroj: The Journal of infection [J Infect] 1998 Nov; Vol. 37 (3), pp. 213-6.
DOI: 10.1016/s0163-4453(98)91828-x
Abstrakt: Objectives: To describe the clinical presentation of HIV disease in older patients.
Methods: In the period 1989-1996 we reviewed the medical records of 100 patients with human immunodeficiency virus (HIV) infection aged 50 years or older and, 197 controls among HIV-infected patients aged 15-40 years, who attended six institutions in the autonomous community of Valencia (Spain).
Results: Older patients were mostly males (86%), men who have sex with men (42%) or unknown (20%) as exposure categories. Older patients had lower CD4 cell counts/mm3 (163+/-136 vs. 450+/-373, P= 0.008), and had AIDS at first evaluation (49% vs. 29%, P = 0.0006) compared with younger patients. For patients presenting with AIDS at HIV infection diagnosis, type and frequency of AIDS indicator diseases did not differ between older and younger patients.
Conclusion: Studies on clues for early detection of HIV infection in patients aged 50 years or older are urgently needed to improve the health care in this population.
Databáze: MEDLINE
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