Autor: |
Massamba NN; The International Centre of Insect Physiology and Ecology, Nairobi, Kenya., Mutinga MJ, Kamau CC |
Jazyk: |
angličtina |
Zdroj: |
Acta tropica [Acta Trop] 1998 Nov 30; Vol. 71 (3), pp. 293-303. |
DOI: |
10.1016/s0001-706x(98)00071-0 |
Abstrakt: |
Using cloned kDNA sequences from the reference strain of Leishmania tropica IC-067, we have screened leishmanial isolates from Laikipia District of Kenya and identified these isolates as L. tropica. One isolate, IC-331, from a rat (Rattus rattus) was typed as L. tropica. This is the first time that L. tropica has been isolated from a wild rodent in Kenya and thus the first indication that the disease caused by L. tropica might be a zoonosis. The leishmanial isolates, especially those of sandflies, display extensive heterogeneity, prompting a need for selecting local and/or regional reference strains to generate species-specific DNA probes for use in identifying field isolates. |
Databáze: |
MEDLINE |
Externí odkaz: |
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