| Autor: |
Zemann BI; School of Veterinary Medicine, Vienna, Austria., Moore AS, Rand WM, Mason G, Ruslander DM, Frimberger AE, Wood CA, L'Heureux DA, Gliatto J, Cotter SM |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of veterinary internal medicine [J Vet Intern Med] 1998 Nov-Dec; Vol. 12 (6), pp. 465-70. |
| DOI: |
10.1111/j.1939-1676.1998.tb02151.x |
| Abstrakt: |
Ninety-eight dogs with lymphoma treated with a 5-drug combination chemotherapy regimen (vincristine, L-asparaginase, cyclophosphamide, doxorubicin, prednisone [VELCAP-L]) were evaluated for pretreatment characteristics predictive for response and remission duration. The complete remission rate was 69%, with a median remission duration of 55 weeks. Dogs with advanced stage of disease, constitutional signs, dogs that were older, and dogs that were dyspneic were less likely to achieve remission. Once in remission, small dogs and dogs without pretreatment thrombocytopenia were likely to have longer remission duration. Toxicoses were frequent, but rarely fatal, and no predictitive factors were found for a dog developing toxicoses. VELCAP-L is an effective treatment for dogs in stage I-III lymphoma, particularly in young, small animals. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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