| Autor: |
Walenkamp GH; Department of Orthopedic Surgery, Academic Hospital Maastricht, The Netherlands., Kleijn LL, de Leeuw M |
| Jazyk: |
angličtina |
| Zdroj: |
Acta orthopaedica Scandinavica [Acta Orthop Scand] 1998 Oct; Vol. 69 (5), pp. 518-22. |
| DOI: |
10.3109/17453679808997790 |
| Abstrakt: |
We treated 100 patients having osteomyelitis with debridement and gentamicin-PMMA beads and followed them for 5 (1-12) years. 66 of the infections were chronic, in 18 cases combined with arthritis and in 3 cases with pseudarthrosis. They underwent 117 "treatment periods", consisting of one or more operations (total 152), in most cases with an interval of 2 weeks. No systemic antibiotics were necessary besides the local antibiotic treatment in 52 of the treatment periods. Healing was achieved in 92 patients, in 78 after a single treatment period which included 1-5 operations, in 14 after two or three treatment periods. Healing was more difficult to achieve when the infection was chronic, especially with a duration of more than 6 years or when caused by elective surgery. Local antibiotic treatment with gentamicin PMMA beads has the advantage that the wound can be closed primarily and that a higher local antibiotic concentration in the tissues can be achieved, often making systemic antibiotic treatment unnecessary. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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