[Ebastine in the treatment of seasonal allergic rhinitis].
| Autor: | Il'ina NI, Balabolkin II, Blokhin BM, Goriachkina LA, Kolganova NA, Pampura AN, Sidorenko IV |
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| Jazyk: | ruština |
| Zdroj: | Terapevticheskii arkhiv [Ter Arkh] 1998; Vol. 70 (9), pp. 79-81. |
| Abstrakt: | Aim: To test the efficiency and tolerance of the second generation antihistamine drug ebastin (kestine) in patients with seasonal allergic rhinitis (SAR). Materials and Methods: Kestin was given for 3 weeks in doses 10 and 20 mg/day to 226 patients with SAR running for 6.8 +/- 6.1 years. SAR symptoms relief, subjective effects, side effects were studied. Results: The total index of rhinitis symptoms diminished from 11.6 to 1.2 scores. Subjective response was registered in 82% of the patients, objective in 77%. Neither treatment aggravations nor serious side effects occurred. 2 patients had drowsiness, head aches, dizziness and discontinued treatment. Conclusion: Kestin is effective in SAR, had no serious side effects, is well tolerated. |
| Databáze: | MEDLINE |
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