Recurrent respiratory papillomatosis.

Autor: Murray LN; Tulane University Medical School, USA., Miller RH
Jazyk: angličtina
Zdroj: The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society [J La State Med Soc] 1998 Oct; Vol. 150 (10), pp. 456-9.
Abstrakt: Recurrent respiratory papillomatosis is a disease characterized by the growth of wart-like neoplasms anywhere along the aerodigestive tract. The etiologic agent is the human papillomavirus, of which 90 subtypes have been described. The age distribution of those affected appears to be a bimodal curve, with the first peak around 5 years of age and the second occurring in adults in the third decade of life. The mainstay of treatment is surgical resection to maintain an adequate airway; patients often require multiple surgeries. The epidemiology, pathogenesis, clinical features, and treatment options are discussed. Current evidence regarding prognosis and the multifactorial nature of pathogenesis are also reviewed.
Databáze: MEDLINE