Does vitamin C reduce blood pressure? Results of a large study of people aged 65 or older.
| Autor: | Bates CJ; Medical Research Council Dunn Nutrition Unit, Cambridge, UK., Walmsley CM, Prentice A, Finch S |
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| Jazyk: | angličtina |
| Zdroj: | Journal of hypertension [J Hypertens] 1998 Jul; Vol. 16 (7), pp. 925-32. |
| DOI: | 10.1097/00004872-199816070-00005 |
| Abstrakt: | Objective: To characterize relationships among blood pressure, pulse rate, vitamin C status and other protective and risk factors for older British people, from a national survey. Design: A cross-sectional analysis of survey data. Setting: A population study, representative of mainland Britain. Subjects: Among 914 people of both sexes living in the community, 373 were taking blood-pressure-lowering drugs and were therefore excluded from the analyses. Interventions: Completion of an interview on health, lifestyle and dietary habits, recording of a 4-day dietary record, anthropometry and taking of a blood sample to determine haematological and biochemical status. Main Outcome Measures: Systolic and diastolic blood pressures, pulse rate, indices of micronutrient status including plasma ascorbate concentration, nutrient intake and haematology. Results: Plasma ascorbate concentration was inversely correlated to systolic and diastolic blood pressures and pulse rate. Other covariates of blood pressure included age, sex, domicile, plasma retinol, fibrinogen and gamma-tocopherol concentrations, erythrocyte count, prothrombin time and urine sodium: creatinine ratio. Covariates of pulse rate included sex, domicile, plasma fibrinogen and platelet count. Blood pressure was also correlated to intake of vitamin C. Conclusions: Plasma ascorbate concentration and intake of vitamin C are covariates of blood pressure in older people living in Britain. New intervention studies are now needed, to test for possible causalities. |
| Databáze: | MEDLINE |
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