| Autor: |
Wilson CJ; Department of Otolaryngology-Head and Neck Surgery, Kansas University Medical Center, Kansas City 66160-7380, USA., Woodroof JM, Girod DA |
| Jazyk: |
angličtina |
| Zdroj: |
The Annals of otology, rhinology, and laryngology [Ann Otol Rhinol Laryngol] 1998 Oct; Vol. 107 (10 Pt 1), pp. 847-50. |
| DOI: |
10.1177/000348949810701006 |
| Abstrakt: |
Octreotide is an 8-chain amino acid analog of somatostatin. Somatostatin and its receptors occur naturally in multiple sites within the body and serve a suppressive role in endocrine hormone release. When octreotide, which has a considerably longer half-life than somatostatin, is combined with a radioactive isotope, receptor-based imaging can be performed to visualize tumors with high concentrations of somatostatin receptors. Tumors of neural crest origin -- pituitary adenomas, islet cell tumors, medullary thyroid carcinomas, pheochromocytomas, carcinoids, and paragangliomas -- all express high levels of somatostatin receptors. We present the first reported positive octreotide scan of a Hürthle cell carcinoma of the thyroid and, more important, discuss the role of octreotide scanning in otolaryngology, which has not yet been reviewed by our literature. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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