[The prognostic importance of the immunohistochemical study of protein p53 in transitional-cell bladder tumors].

Autor: Gaĭyrov AG, Romanenko AM, Klimenko IA, Sakalo VS, Grigorenko VN, Nepomniashchiĭ VN
Jazyk: ruština
Zdroj: Likars'ka sprava [Lik Sprava] 1998 Jul-Aug (5), pp. 86-9.
Abstrakt: In an immunohistochemical investigation designed to study a mutated p53 protein in transitional-cell tumours (n = 44) we succeeded in identifying the presence of two types of transitional-cell tumours of human urinary bladder, such as p53 immunopositive and p53 immunonegative transitional-cell tumours. Thus, the results of the immunohistochemical investigation into the protein p53 were found out to directly correlate with the clinical course of transitional-cell tumours, that are held to be of great differential-diagnostic and prognostic significance.
Databáze: MEDLINE