Autor: |
Samoĭlovich EO; Research Institute of Microbiology and Epidemiology, Republican Centre of Hygiene and Epidemiology, Minsk, Republic of Belarus., Kapustik LA, Fel'dman EV, Ermolovich MA, Svirchevskaia EIu, Titov LP, Zakharenko DF, Belova EIu, Chernovetskiĭ MA, Korostik TS |
Jazyk: |
ruština |
Zdroj: |
Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 1998 Jul-Aug (4), pp. 36-40. |
Abstrakt: |
In 1996 the immunization of children against measles, mumps and rubella with combined vaccine Trimovax ("Pasteur Mérieux Connaught", France) was carried out in the Republic of Belarus. The reactogenicity of the vaccine was studied in 372 children. To evaluate immunological effectiveness, the sera of 324 children were used. Postvaccinal reactions of different intensity were registered in 5.6% of the children; of these, 1.3% exhibited severe reactions. Among the vaccinees, protective titers of antibodies to measles were found in 97.6% to mumps, in 93.8% and to rubella, in 96.0% of the children. Antibodies to all three components of the vaccine were present mainly in high and moderate titers. The results thus obtained indicate that, Trimovax was well tolerated and proved to be immunologically active. |
Databáze: |
MEDLINE |
Externí odkaz: |
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