Autor: |
Servent D; Département d'Ingénierie et d'Etudes des Proteines, CEA-Saclay, Gif-sur-Yvette, France., Thanh HL, Antil S, Bertrand D, Corringer PJ, Changeux JP, Ménez A |
Jazyk: |
angličtina |
Zdroj: |
Journal of physiology, Paris [J Physiol Paris] 1998 Apr; Vol. 92 (2), pp. 107-11. |
DOI: |
10.1016/s0928-4257(98)80146-0 |
Abstrakt: |
Snakes and cone snails produce toxins which block muscular and/or neuronal nicotinic acetylcholine receptors (AChRs). This paper mostly focuses on the determinants by which a snake long chain curaremimetic toxin and the cone snail toxin ImI bind specifically to the alpha 7 neuronal receptor. In both cases, the site involves a small turn-like structure constrained by two half-cystines. |
Databáze: |
MEDLINE |
Externí odkaz: |
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