| Autor: |
Rico Cordeiro O; Instituto de Medicina Tropical Pedro Kouri., Bravo González JR, Díaz González M |
| Jazyk: |
Spanish; Castilian |
| Zdroj: |
Revista cubana de medicina tropical [Rev Cubana Med Trop] 1994; Vol. 46 (2), pp. 94-8. |
| Abstrakt: |
The effectiveness or post-license efficacy of the BC antimeningococcal vaccine (VA-MENGOC-BC) was assessed 1 year after the end of the immunization campaign in children aged 0 to 5 years. Occurrence of the disease before and after intervention is described and effectiveness is estimated following the recommendations described by Orenstein et al. We used 2 case definitions to compare results in groups formed following different criteria, according to the employed diagnostic tests. Two formulas are used to assess efficacy: one, estimating the rates among vaccinated and non-vaccinated; and the other one, estimating the ratio of cases per vaccinated population. The increase of the relative annual decrease of the incidence occurring since 1985--a decrease of 10% or less--which in 1990 reached 34.6% should be stressed; the ratio of new cases prevented by the intervention was higher than 75%. Effectiveness or post-license efficacy was close to 90%, independently from the case definition variant or formula employed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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