[Elevation of serum glucose concentration after administration of 5'-AMP to rats and modulation of this process dynamics following single gamma-irradiation at 1 Gy dose].

Autor: Koltun VV; Institute of Radiobiology, Academy of Sciences of Belarus, Minsk., Egutkin GG, Gatsko GG
Jazyk: ruština
Zdroj: Radiatsionnaia biologiia, radioecologiia [Radiats Biol Radioecol] 1998 Jul-Aug; Vol. 38 (4), pp. 547-51.
Abstrakt: Injection of exogenic 5'-AMP to rats was accompanied by pronounced and transient adenosinemediated elevation of serum glucose concentration. Both efficiency and duration of the observed hyperglycemic effect were increased within the first week after single whole-body gamma-irradiation (137Cs) of the animals at 1 Gy dose. These data suggest modification of purinergic regulation of some processes of carbohydrate metabolism and disturbance of the organism tolerance towards the glucose following 1 Gy gamma-irradiation.
Databáze: MEDLINE