[Can radioactive iodine be used in the treatment of diffuse non-toxic goiter?].

Autor: Nygaard B; Endokrinologisk afdeling F, Amtssygehuset i Herlev., Hegedüs L, Bennedbaek FN, Veje A, Faber JO, Hansen JE
Jazyk: dánština
Zdroj: Ugeskrift for laeger [Ugeskr Laeger] 1998 Sep 07; Vol. 160 (37), pp. 5349-52.
Abstrakt: Traditional treatment modalities of diffuse nontoxic goitre are thyroid hormone suppression or surgery. When treating nodular nontoxic goitre with 131I treatment, a reduction in thyroid volume to about 50% is seen. In the present study we evaluated the effect of 131I treatment in 21 patients treated for a diffuse nontoxic goitre and followed by evaluation of thyroid volume measured by ultrasound. Thyroid volume declined in all patients from median of 66 ml (range 27-160 ml) to 21 ml (9-108 ml) over a year, a reduction of 62%. Three patients developed hypothyroidism in the follow-up period (14%), one of these had a temporary hyperthyroid fase. In conclusion, 131I treatment of diffuse nontoxic goitre reduces thyroid volume by approximately 60% within 12 months. Hypothyroidism developed in 14% during a limited follow-up period.
Databáze: MEDLINE