Neurotoxicity caused by valacyclovir in a patient on hemodialysis.

Autor: Linssen-Schuurmans CD; Hospital Gelderse Vallei, Bennekom, Netherlands., van Kan EJ, Feith GW, Uges DR
Jazyk: angličtina
Zdroj: Therapeutic drug monitoring [Ther Drug Monit] 1998 Aug; Vol. 20 (4), pp. 385-6.
DOI: 10.1097/00007691-199808000-00005
Abstrakt: The authors report toxicity caused by valacyclovir in a patient on hemodialysis. After initial recuperation resulting from treatment with hemodialysis, the patient experienced a relapse of neurologic symptoms, again necessitating hemodialysis. Although acyclovir and its analogues are generally safe drugs, they should be used with caution in patients with end-stage renal disease. Therapeutic drug monitoring may be indicated.
Databáze: MEDLINE