| Autor: |
Selimova LM, Bobkov AF, Serebrovskaia LV, Kravchenko AV, Liubaeva EV, Kazennova EV, Sankov MN, Pokrovskiĭ VV |
| Jazyk: |
ruština |
| Zdroj: |
Voprosy virusologii [Vopr Virusol] 1998 May-Jun; Vol. 43 (3), pp. 110-3. |
| Abstrakt: |
Human immunodeficiency type 1 virus env subtype B 95RU25B isolated from a Russian citizen is studied. The time course of clinical changes and immunological parameters over 5.5 years is presented. Phenotypical characteristics of the isolate were assessed by culturing in different sensitive cell cultures. Genotyping by the heteroduplex analysis and env gene sequencing were carried out. 95RU25B variant is capable of infecting a wide spectrum of cell cultures and by the type of replication can be classified with the S/L.3 group. The phenotypical properties of the isolate apparently determine the characteristic features in the primary structure of V3 loop. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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