| Autor: |
Klebanoff MA; Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, National Instiutes of Health, Bethesda, MD 20892-7510, USA., Levine RJ, Clemens JD, DerSimonian R, Wilkins DG |
| Jazyk: |
angličtina |
| Zdroj: |
American journal of epidemiology [Am J Epidemiol] 1998 Aug 01; Vol. 148 (3), pp. 259-62. |
| DOI: |
10.1093/oxfordjournals.aje.a009633 |
| Abstrakt: |
Although during pregnancy there is a better correlation between maternal serum cotinine concentration and adverse outcome than between self-reported smoking and such an outcome, few studies of pregnancy have measured cotinine concentration to determine how much a woman smokes. This study assessed the accuracy of self-reported smoking during pregnancy by performing serum cotinine assays on 448 women registered in the Collaborative Perinatal Project (1959-1966). Based on the assumption that a serum cotinine concentration of >10 ng/ml represented active smoking, 94.9% of women who denied smoking and 87.0% of women who stated that they smoked (kappa=0.83) reported their status accurately. Among smokers, the correlation coefficient between cotinine concentration and number of cigarettes smoked per day was 0.44. Serum cotinine concentration correlated more strongly than self-reported smoking with infant birth weight (r=0.246 vs. 0.200). In conclusion, this study showed that pregnant women accurately reported whether they smoked, but cotinine concentration was a better measure than self-report of the actual tobacco dose received. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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