| Autor: |
Marks GJ; Department of Surgery, Allegheny University of the Health Sciences, Philadelphia, PA 19102-1192, USA., Marks JH, Mohiuddin M, Brady L |
| Jazyk: |
angličtina |
| Zdroj: |
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer [Recent Results Cancer Res] 1998; Vol. 146, pp. 161-74. |
| DOI: |
10.1007/978-3-642-71967-7_15 |
| Abstrakt: |
High-dose preoperative radiation and specifically designed surgical techniques were used to extend the application of sphincter preservation surgery for cancer of the distal 3 cm of the true rectum. A total of 203 consecutive patients with rectal cancer were treated with external-beam irradiation (45-70 Gy) and radical curative surgery. The cancer was at the level of 0.5-3.0 cm in 65 patients. In these 65 patients treated by radical resection with coloanal anastomosis six suffered recurrence (9%), and the 5-year actuarial survival was 85%. There was a single death. There was no local recurrence among 44 patients in whom the postradiated cancer resided in the rectal wall with or without nodal involvement. With proper selection, high-dose preoperative radiation therapy thus permits extended use of sphincter preservation surgery with coloanal anastomosis for cancers of the distal 3 cm of the true rectum. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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