| Autor: |
Chu MY; Department of Medicine and Clinical Pharmacology, Brown University and Rhode Island Hospital, Providence 02903, USA., Lipsky MH, Yee LK, Epstein J, Whartenby KA, Freeman S, Chen TM, Chu E, Forman EN, Calabresi P |
| Jazyk: |
angličtina |
| Zdroj: |
Pharmacology [Pharmacology] 1998 Jun; Vol. 56 (6), pp. 318-26. |
| DOI: |
10.1159/000028216 |
| Abstrakt: |
An in vivo experimental model was developed to predict efficiently and accurately chemosensitivity of human tumors. Human cancer cells either from cultured cell lines or from patients' tumors were injected directly into semipermeable polysulfone fibers subsequently implanted into immunocompetent rats. Results suggest utility of this novel model system for predicting tumor sensitivity to a wide range of anticancer agents and for potentially guiding the treatment of cancer patients in the clinical setting. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
