| Autor: |
Trekova NA; Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow., Khlopushina TG, Basharova LA, Vetrilé LA, Mikovskaia OI, Evseev VA |
| Jazyk: |
ruština |
| Zdroj: |
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova [Zh Vyssh Nerv Deiat Im I P Pavlova] 1998 Mar-Apr; Vol. 48 (2), pp. 251-9. |
| Abstrakt: |
Mice of C57BL/6 strain were singly injected intraperitoneally with antibodies (AB) to serotonin (5-HT). The "open-field" testing in different periods after the AB injection revealed a depression of behavior within 1.5 h which changed for activation within 1 day and, again, depression within 5 days after the injection. The analysis of neurotransmitter content in the sensorimotor cortex and hypothalamus revealed increased levels of serotonin and, especially, dopamine in the cortex within 1 day. The cortex serotonin level within 5 days was also increased. The possible mechanisms are discussed of neurotropic action of AB to 5-HT. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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