Haemolytic-uraemic syndrome outbreak caused by Escherichia coli O111:H-: clinical outcomes.

Autor: Henning PH; Department of Nephrology, Women's and Children's Hospital, Adelaide, SA. henningp@wch.gov.sa.au, Tham EB, Martin AA, Beare TH, Jureidini KF
Jazyk: angličtina
Zdroj: The Medical journal of Australia [Med J Aust] 1998 Jun 01; Vol. 168 (11), pp. 552-5.
DOI: 10.5694/j.1326-5377.1998.tb139083.x
Abstrakt: In South Australia in 1995, we treated 20 children with haemolytic-uraemic syndrome associated with Escherichia coli O111:H-. The source of the outbreak was contaminated locally produced semi-dry fermented sausage (mettwurst). One child died of multiple haemorrhagic cerebral infarcts. Eighteen children required renal dialysis (for a median of 14 days); 12 months after discharge five still had significant impairment of renal function. Other major complications included colonic necrosis (3), cerebral haemorrhage/infarction (3), convulsions (4), and glucose intolerance (2). Although E. coli O111:H- has been associated with sporadic cases of haemolytic-uraemic syndrome, this was the first large outbreak reported in Australia.
Databáze: MEDLINE