[Asthma associated with gastroesophageal reflux].

Autor: González Morales JE; Clínica de Asma del servicio de neumología, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, NL, México., Leal de Hernández L, González Spencer D
Jazyk: Spanish; Castilian
Zdroj: Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) [Rev Alerg Mex] 1998 Jan-Feb; Vol. 45 (1), pp. 16-21.
Abstrakt: Objective: In order to explore the association between poorly controllable asthma and gastroesophageal reflux (GER), a prospective clinical trial is presented.
Material and Method: This trial included 28 patients with negative atopic indicators who presented difficulty in the management of their disease. All patients underwent a complete medical history as well as skin tests for common airborne allergens, total serum IgE, peripheral blood eosinophils, spirometry, chest X-ray and esophageal barium films. Additionally, esophageal endoscopy was performed on 9 patients, and esophageal manometry in 1 patient. All were submitted to antireflux therapy and received omeprazole and cisapride for 8 weeks.
Results: Complete improvement was observed in 24 patients (85.7%), moderate improvement in 3 patients (10.7%), and no improvement in 1 patient (3.6%). Three patients required antireflux surgery.
Conclusions: Symptoms reappeared 2-3 weeks after suspending treatment, which led to the recommendation that antireflux measures become a way of life for these patients.
Databáze: MEDLINE
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